What
Autologous hematopoietic stem cell transplantation typically begins with drug mobilization to move hematopoietic stem cells into the peripheral blood; these are then collected using apheresis equipment and cryopreserved. After evaluation, high-dose chemotherapy is administered as preconditioning to reduce the tumor burden and create space for hematopoiesis, followed by reinfusion of the previously stored stem cells. During treatment, blood counts, infection, and organ function are routinely monitored, with blood transfusions, anti-infection measures, and nutritional support provided as needed. The overall goal is to promote hematopoietic reconstitution and a smooth discharge. The above is general health information, not medical advice; specific details are subject to specialist evaluation and hospital protocols.
How
- Use medication to mobilize cells into the peripheral blood.
- Collect and cryopreserve hematopoietic stem cells.
- Administer high-dose chemotherapy for preconditioning.
- Reinfuse the preserved stem cells to reconstruct hematopoiesis.
- Monitor blood counts and infection and provide supportive care.
Recovery
In the early post-infusion period, the focus is on monitoring blood counts, temperature, bleeding, and signs of infection, with blood transfusions, anti-infection measures, and growth factor support provided as needed. Diet is gradually transitioned, with attention to oral and skin care and reduced exposure to crowded environments. Doctors arrange periodic follow-up to assess hematopoietic reconstitution and disease control. Whether air travel is permitted is subject to clinical assessment; carry a discharge summary and medication list, and if a catheter is in place, pay attention to care and security communication when traveling.
- Monitor blood counts, temperature, and signs of infection early on.
- Gradually resume diet and perform oral care.
- Arrange follow-up to assess hematopoietic reconstitution as directed by the doctor.
FAQ
Will it affect fertility?
High-dose chemotherapy may affect fertility. Options such as embryo/sperm/egg preservation can be discussed with the doctor before transplantation.
Does ASCT require a donor?
As it is an autologous transplant, it usually uses the patient's own stem cells and does not require an external donor; it is still necessary to confirm whether successful mobilization and collection are possible.
What are the common risks?
Possible complications include bone marrow suppression, infection, bleeding, mucositis, and fluctuations in organ function; medical staff will monitor and provide supportive care.
When can I get vaccinated?
Vaccinations need to be arranged sequentially after specialist evaluation. Do not self-administer vaccinations. The timing depends on hematopoietic reconstitution and immune recovery.
What are the components of the cost?
Includes evaluation, collection, preconditioning, and inpatient care; management of complications, non-standard consumables, and extended hospitalization may be charged separately. See "Medical Expenses in China" above for details.
How long does the whole process take?
From evaluation, mobilization and collection to hospitalization, it commonly takes weeks to months, depending on individual recovery and hospital scheduling.
What should I pay attention to in terms of diet and daily life?
Pay attention to oral hygiene and skin care, eat clean and cooked food, and try to avoid crowded places and contact with sick people.